The MPS VI Clinical Surveillance Program (MPS VI CSP) Participate in the MPS VI CSP: 866-906-6100 BioMarin Pharmaceutical Inc. encourages participation in confidential data collection for the MPS VI Clinical Surveillance Program (CSP). The MPS VI CSP is an ongoing observational program designed to collect information about the progression of the disease and medical outcomes of people with MPS VI. Since MPS VI is rare, the information gathered will help physicians learn from the collective experience of others, so they may better understand, treat, and manage MPS VI. The goal is for all individuals with MPS VI to be a part of the program. Treatment with NAGLAZYME® (galsulfase) is not a prerequisite for participation. Advancing MPS VI treatment and research Provides a resource to physicians and patients for optimizing patient care Enriches the clinical community’s understanding of MPS VI Evaluates long-term safety and efficacy of NAGLAZYME The first comprehensive MPS VI resource for physicians Establishes the first comprehensive resource for understanding the variability and progression of MPS VI, as well as the long-term safety and efficacy of the only ERT indicated for its treatment Collects data from multiple centers around the world to compile in an observational database A database of longitudinal data, available to participating physicians Optimizing patient care Consolidates data to develop new patient-monitoring standards Reports patient outcomes Provides new understanding for optimizing patient care Recommended assessments reflect a high standard of patient care based on global feedback from MPS VI experts Easy participation for both physician and patient Participation in the CSP is voluntary No experimental treatments or assessments The only requirements to enroll a patient are a confirmed diagnosis of MPS VI, appropriate institutional approval, and patient or legal guardian consent Data collected for the program include standard assessments that most physicians are already recording For enrollment support/information, call 866-906-6100 or e-mail bpps@bmrn.com